Indexing Multiple Columns and Using the `.fillna()` Command

What You Will Learn

In this tutorial, you will master the art of indexing multiple columns in a DataFrame and leveraging the .fillna() method to efficiently handle missing values.

Introduction to the Problem and Solution

Encountering missing data is a common challenge when working with datasets in Python. The .fillna() method comes to the rescue by allowing us to replace these missing values with specific values. Moreover, by selecting multiple columns, we can focus on subsets of our data for targeted analysis.

To tackle this issue effectively, we will showcase how to pinpoint multiple columns within a DataFrame and strategically apply the .fillna() method to address missing data in those columns.


import pandas as pd

# Sample DataFrame
data = {'A': [1, 2, None], 'B': [None, 5, 6], 'C': [7, 8 ,9]}
df = pd.DataFrame(data)

# Fill missing values in columns A and B with 0
columns_to_fill = ['A', 'B']
df[columns_to_fill] = df[columns_to_fill].fillna(0)

# Display the updated DataFrame

# Copyright PHD



  • Import the pandas library as pd.
  • Create a sample DataFrame with missing values.
  • Specify a list of column names (columns_to_fill) to be filled.
  • Utilize df[columns_to_fill].fillna(0) to replace NaN values in selected columns.
  • Print out the DataFrame post filling missing values.
    How can I fill all missing values in a DataFrame?

    You can use df.fillna(value), where value denotes the replacement for NaN values.

    Can I specify different replacement values for different columns?

    Yes, by passing a dictionary mapping column names to their respective replacement value while using .fillna().

    Is it possible to drop rows or columns instead of filling NaNs?

    Absolutely. Employ the dropna() function to eliminate rows or columns based on null values.

    Does inplace=True update my original DataFrame directly?

    Setting inplace=True parameter modifies your existing dataframe directly without returning anything new; it updates the object in place.

    How do I handle missing categorical data?

    For categorical data types, consider replacing NaNs with the mode (most frequent value) of each column containing categorical variables.

    Can I interpolate instead of filling NaNs?

    Yes! Pandas offers an .interpolate() method enabling linear interpolation between known points for handling missing values.


    Effectively managing missing data is vital during data exploration and model development stages. By mastering techniques like indexing multiple columns and utilizing tools such as .fillna(), you equip yourself with essential skills for preparing clean datasets crucial for further analysis or machine learning tasks proficiently.

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